Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety.

Sustained-release lidocaine sheet for pain following tooth extraction: A randomized, single-blind, dose-response, controlled, clinical study of efficacy and safety.

BACKGROUND:We have synthesized a sustained-release lidocaine sheet (SRLS) using biodegradable polymers and previously demonstrated its safety and long-term analgesic effect in the normal mucous membrane of healthy human volunteers. OBJECTIVES:The aim of this clinical study was to evaluate the effica...

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Bibliographic Details
Main Authors: Toshiyuki Suzuki, Kensuke Kosugi, Takashi Suto, Masaru Tobe, Yasuhiko Tabata, Satoshi Yokoo, Shigeru Saito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6028143?pdf=render

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