Anti-Virulence Strategy against the Honey Bee Pathogenic Bacterium <i>Paenibacillus larvae</i> via Small Molecule Inhibitors of the Bacterial Toxin Plx2A

Anti-Virulence Strategy against the Honey Bee Pathogenic Bacterium <i>Paenibacillus larvae</i> via Small Molecule Inhibitors of the Bacterial Toxin Plx2A

American Foulbrood, caused by <i>Paenibacillus larvae</i>, is the most devastating bacterial honey bee brood disease. Finding a treatment against American Foulbrood would be a huge breakthrough in the battle against the disease. Recently, small molecule inhibitors against virulence facto...

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Bibliographic Details
Main Authors: Julia Ebeling, Franziska Pieper, Josefine Göbel, Henriette Knispel, Michael McCarthy, Monica Goncalves, Madison Turner, Allan Rod Merrill, Elke Genersch
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Toxins
Subjects:
ADP-ribosylation
small molecule inhibitor
anti-virulence strategy
bacterial toxin
virulence factor
<i>Paenibacillus larvae</i>
Online Access:https://www.mdpi.com/2072-6651/13/9/607

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