Iron chelating properties of Eltrombopag: Investigating its role in thalassemia-induced osteoporosis.
Chronic blood transfusions are responsible to cause iron overload, which leads to several complications to end organs and osteoporosis. Iron chelation is needed to remove iron excess and to contain bone-mass loss. Deferasirox is the most recent oral iron chelator that prevents transfusion related ir...
Main Authors: | Francesca Punzo, Chiara Tortora, Maura Argenziano, Maddalena Casale, Silverio Perrotta, Francesca Rossi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0208102 |
Similar Items
-
Effects of Eltrombopag on In Vitro Macrophage Polarization in Pediatric Immune Thrombocytopenia
by: Alessandra Di Paola, et al.
Published: (2021-12-01) -
The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma
by: Francesca Rossi, et al.
Published: (2019-04-01) -
CB2 Receptor Stimulation and Dexamethasone Restore the Anti-Inflammatory and Immune-Regulatory Properties of Mesenchymal Stromal Cells of Children with Immune Thrombocytopenia
by: Francesca Rossi, et al.
Published: (2019-02-01) -
Cannabinoid Receptor Type 2: A Possible Target in SARS-CoV-2 (CoV-19) Infection?
by: Francesca Rossi, et al.
Published: (2020-05-01) -
IRON CHELATION THERAPY IN THALASSEMIA SYNDROMES
by: Paolo Cianciulli
Published: (2009-06-01)