Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model.

Cyclosporine A eyedrops with self-nanoemulsifying drug delivery systems have improved physicochemical properties and efficacy against dry eye disease in a murine dry eye model.

<h4>Purpose</h4>We aimed to compare the physicochemical properties and in vivo efficacy of commercially available nanoemulsion cyclosporine A (CsA) eyedrops in benzalkonium chloride (BAC)-induced dry eye disease (DED).<h4>Methods</h4>Particle size analysis was performed on co...

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Bibliographic Details
Main Authors: Seung Pil Bang, Chang Yeor Yeon, Nirpesh Adhikari, Sanjiv Neupane, Harim Kim, Dong Cheol Lee, Myeong Jin Son, Hyun Gyo Lee, Jae-Young Kim, Jong Hwa Jun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224805

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