Inhibition of Stromal PlGF Suppresses the Growth of Prostate Cancer Xenografts

Inhibition of Stromal PlGF Suppresses the Growth of Prostate Cancer Xenografts

The growth and vascularization of prostate cancer is dependent on interactions between cancer cells and supporting stromal cells. The primary stromal cell type found in prostate tumors is the carcinoma-associated fibroblast, which produces placental growth factor (PlGF). PlGF is a member of the vasc...

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Bibliographic Details
Main Authors: Dietmar Abraham, Seyedhossein Aharinejad, Mouldy Sioud, Trevor Lucas, Anita Thomas, Karin Zins
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer
placental growth factor
xenograft model
tumor-host interaction
tumor angiogenesis
Online Access:http://www.mdpi.com/1422-0067/14/9/17958

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