CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia
The utility of CRISPR-Cas9 to repair or reverse diseased states that arise from recent genetic mutations in the human genome is now widely appreciated. The use of CRISPR to “design” the outcomes of biology is challenged by both specialized ethicists and the general public. Less of a focus, however,...
Main Authors: | Lais de Lima Balico, Eric A. Gaucher |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | Molecular Therapy: Nucleic Acids |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253121001967 |
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