Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis

Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis

The interaction and crosstalk of Toll-like receptors (TLRs) is an established pathway in which the innate immune system recognises and fights pathogens. In a single nucleotide polymorphisms (SNP) analysis of an Indian cohort, we found evidence for both TLR4-399T and TRL8-1A conveying increased susce...

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Bibliographic Details
Main Authors: Shruthi Thada, Gabor L. Horvath, Mario M. Müller, Nickel Dittrich, Melanie L. Conrad, Saubashya Sur, Abid Hussain, Karin Pelka, Suman Latha Gaddam, Eicke Latz, Hortense Slevogt, Ralf R. Schumann, Sanne Burkert
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
TLR4
TLR8
tuberculosis
SNP analysis
heterodimerisation
Online Access:https://www.mdpi.com/1422-0067/22/4/1560

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