Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails

Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails

Abstract Background The advent of human-induced pluripotent stem cells holds great promise for producing ample individualized hepatocytes. Although previous efforts have succeeded in generating hepatocytes from human pluripotent stem cells in vitro by viral-based expression of transcription factors...

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Bibliographic Details
Main Authors: Cong Du, Yuan Feng, Dongbo Qiu, Yan Xu, Mao Pang, Nan Cai, Andy Peng Xiang, Qi Zhang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
Hepatocyte differentiation
Human pluripotent stem cells
Small molecules
Online Access:http://link.springer.com/article/10.1186/s13287-018-0794-4

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