Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer

Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer

Inhibiting DNA synthesis is an important therapeutic strategy that is widely used to treat a number of hyperproliferative diseases including viral infections, autoimmune disorders, and cancer. This chapter describes two major categories of therapeutic agents used to inhibit DNA synthesis. The first...

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Bibliographic Details
Main Author:	Anthony J. Berdis
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-11-01
Series:	Frontiers in Molecular Biosciences
Subjects:	DNA polymerases chemotherapy nucleoside analogs DNA damaging agents cancer
Online Access:	http://journal.frontiersin.org/article/10.3389/fmolb.2017.00078/full

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