Modeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologue.

The leucine transporter (LeuT) has recently commanded exceptional attention due mainly to two distinctions; it provides the only crystal structures available for a protein homologous to the pharmacologically relevant neurotransmitter: sodium symporters (NSS), and, it exhibits a hallmark 5-TM inverte...

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Bibliographic Details
Main Authors: Saher Afshan Shaikh, Emad Tajkhorshid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20865057/pdf/?tool=EBI