Destaining of Diff-Quik stained cytologic smears is not necessary for the detection of anaplastic lymphoma kinase gene rearrangement in lung adenocarcinoma by fluorescence in situ hybridization

Destaining of Diff-Quik stained cytologic smears is not necessary for the detection of anaplastic lymphoma kinase gene rearrangement in lung adenocarcinoma by fluorescence in situ hybridization

Background: Anaplastic lymphoma kinase (ALK) gene rearrangement analysis by fluorescence in situ hybridization (FISH) is one of the standard molecular tests for targeted therapy of lung adenocarcinoma. However, insufficient cell block cellularity may impede molecular testing. A recent study showed t...

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Bibliographic Details
Main Authors: Weisheng Xu, Kamal K Khurana, Jamie Tull, Charlene Maciak, Shengle Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Cytology
Subjects:
Anaplastic lymphoma kinase (ALK); cytology smear; Diff-Quik (DQ); fluorescence in situ hybridization (FISH); lung adenocarcinoma
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2016;volume=33;issue=3;spage=154;epage=158;aulast=Xu

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