Increased error-free DNA repair gene expression through reprogramming in human iPS cells

Introduction: Many studies have reported that human-induced pluripotent stem (hiPS)/embryonic stem (hES) cells have an exceptional ability to repair damaged DNA. Moreover, unlike differentiated cells, hES cells have features and mechanisms such as apoptosis-prone mitochondria, which prevent any chan...

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Bibliographic Details
Main Author: Yasuhide Yoshimura
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320418301019