The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells

The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells

The <i>SCN4B</i> gene, coding for the Na<sub>V</sub>β4 subunit of voltage-gated sodium channels, was recently found to be expressed in normal epithelial cells and down-regulated in several cancers. However, its function in normal epithelial cells has not been characterized. I...

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Bibliographic Details
Main Authors: Adélaïde Doray, Roxane Lemoine, Marc Severin, Stéphanie Chadet, Osbaldo Lopez-Charcas, Audrey Héraud, Christophe Baron, Pierre Besson, Arnaud Monteil, Stine Falsig Pedersen, Sébastien Roger
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
Na<sub>V</sub>β4
epithelial phenotype
β-catenin
epithelial-to-mesenchymal transition
mammary cells
Online Access:https://www.mdpi.com/2073-4409/10/7/1624

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