Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients’ Upper and Lower Airways after IV-Antibiotic Therapy

Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients’ Upper and Lower Airways after IV-Antibiotic Therapy

Background. In cystic fibrosis (CF) the upper (UAW) and lower airways (LAW) are reservoirs for pathogens like Pseudomonas aeruginosa. The consecutive hosts’ release of proteolytic enzymes contributes to inflammation and progressive pulmonary destruction. Objectives were to assess dynamics of proteas...

Full description

Bibliographic Details
Main Authors: Ulrike Müller, Julia Hentschel, Wibke K. Janhsen, Kerstin Hünniger, Uta-Christina Hipler, Jürgen Sonnemann, Wolfgang Pfister, Klas Böer, Thomas Lehmann, Jochen G. Mainz
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/626530

Similar Items

Similar Items