Spironolactone in pulmonary arterial hypertension: results of a cross-over study

The renin–angiotensin–aldosterone system is implicated in the pathophysiology of pulmonary arterial hypertension. We undertook this study to determine the effects of spironolactone, a mineralocorticoid receptor blocker, on collagen metabolism in pulmonary arterial hypertension patients. After obtain...

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Bibliographic Details
Main Authors: Zeenat Safdar, Adaani Frost, Arya Basant, Anita Deswal, E. O’Brian Smith, Mark Entman
Format: Article
Language:English
Published: SAGE Publishing 2020-04-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894019898030