Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats

Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats

The hypothalamus-pituitary-adrenal axis (HPA) is the main regulator of the stress response. The key of the HPA is the parvocellular paraventricular nucleus of the hypothalamus (pPVN) controlled by higher-order limbic stress centers. The reactivity of the HPA axis is considered to be a function of ag...

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Bibliographic Details
Main Authors: László Ákos Kovács, Josef Andreas Schiessl, Anna Elisabeth Nafz, Valér Csernus, Balázs Gaszner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
restraint stress
corticosterone
aging
stress response
amygdala
bed nucleus of stria terminalis
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00248/full

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