Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells

Introduction: Orf virus (ORFV) is a prototype Parapoxvirus species in the Poxviridae family that causes serious zoonotic infectious disease. Goat skin fibroblast (GSF) cells are the major host targets of ORFV. Interleukin 8 (IL-8) and tumour necrosis factor (TNF)-α are known to play a vital role in...

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Main Authors: Wang Lingling, Lu Bingzhou, Zheng Haixue, Zhang Keshan, Liu Xiangtao
Format: Article
Language:English
Published: Sciendo 2016-09-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.1515/jvetres-2016-0036
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spelling doaj-06c650b3d54d41e087e9417c4414b53a2021-09-06T19:40:54ZengSciendoJournal of Veterinary Research2450-86082016-09-0160323924310.1515/jvetres-2016-0036jvetres-2016-0036Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cellsWang Lingling0Lu Bingzhou1Zheng Haixue2Zhang Keshan3Liu Xiangtao4State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, ChinaState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, ChinaState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, ChinaState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, ChinaState Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, ChinaIntroduction: Orf virus (ORFV) is a prototype Parapoxvirus species in the Poxviridae family that causes serious zoonotic infectious disease. Goat skin fibroblast (GSF) cells are the major host targets of ORFV. Interleukin 8 (IL-8) and tumour necrosis factor (TNF)-α are known to play a vital role in immune response during viral infections. However, the manner of variation over time of their level of expression in GSF cells remains unclear.https://doi.org/10.1515/jvetres-2016-0036goat skin fibroblastsorf viruscytokines
collection DOAJ
language English
format Article
sources DOAJ
author Wang Lingling
Lu Bingzhou
Zheng Haixue
Zhang Keshan
Liu Xiangtao
spellingShingle Wang Lingling
Lu Bingzhou
Zheng Haixue
Zhang Keshan
Liu Xiangtao
Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
Journal of Veterinary Research
goat skin fibroblasts
orf virus
cytokines
author_facet Wang Lingling
Lu Bingzhou
Zheng Haixue
Zhang Keshan
Liu Xiangtao
author_sort Wang Lingling
title Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
title_short Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
title_full Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
title_fullStr Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
title_full_unstemmed Parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
title_sort parapoxvirus orf virus infection induces an increase in interleukin-8, tumour necrosis factor-α, and decorin in goat skin fibroblast cells
publisher Sciendo
series Journal of Veterinary Research
issn 2450-8608
publishDate 2016-09-01
description Introduction: Orf virus (ORFV) is a prototype Parapoxvirus species in the Poxviridae family that causes serious zoonotic infectious disease. Goat skin fibroblast (GSF) cells are the major host targets of ORFV. Interleukin 8 (IL-8) and tumour necrosis factor (TNF)-α are known to play a vital role in immune response during viral infections. However, the manner of variation over time of their level of expression in GSF cells remains unclear.
topic goat skin fibroblasts
orf virus
cytokines
url https://doi.org/10.1515/jvetres-2016-0036
work_keys_str_mv AT wanglingling parapoxvirusorfvirusinfectioninducesanincreaseininterleukin8tumournecrosisfactoraanddecoriningoatskinfibroblastcells
AT lubingzhou parapoxvirusorfvirusinfectioninducesanincreaseininterleukin8tumournecrosisfactoraanddecoriningoatskinfibroblastcells
AT zhenghaixue parapoxvirusorfvirusinfectioninducesanincreaseininterleukin8tumournecrosisfactoraanddecoriningoatskinfibroblastcells
AT zhangkeshan parapoxvirusorfvirusinfectioninducesanincreaseininterleukin8tumournecrosisfactoraanddecoriningoatskinfibroblastcells
AT liuxiangtao parapoxvirusorfvirusinfectioninducesanincreaseininterleukin8tumournecrosisfactoraanddecoriningoatskinfibroblastcells
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