Licochalcone A, a Polyphenol Present in Licorice, Suppresses UV-Induced COX-2 Expression by Targeting PI3K, MEK1, and B-Raf

Licochalcone A, a Polyphenol Present in Licorice, Suppresses UV-Induced COX-2 Expression by Targeting PI3K, MEK1, and B-Raf

Licorice is a traditional botanical medicine, and has historically been commonly prescribed in Asia to treat various diseases. Glycyrrhizin (Gc), a triterpene compound, is the most abundant phytochemical constituent of licorice. However, high intake or long-term consumption of Gc has been associated...

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Bibliographic Details
Main Authors: Nu Ry Song, Jong-Eun Kim, Jun Seong Park, Jong Rhan Kim, Heerim Kang, Eunjung Lee, Young-Gyu Kang, Joe Eun Son, Sang Gwon Seo, Yong Seok Heo, Ki Won Lee
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:International Journal of Molecular Sciences
Subjects:
Licochalcone A, Solar ultraviolet, Cyclooxygenase-2, PI3K, MEK1, B-Raf
Online Access:http://www.mdpi.com/1422-0067/16/3/4453

Internet

http://www.mdpi.com/1422-0067/16/3/4453

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