In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines

In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines

<p>Abstract</p> <p>Purpose</p> <p>The CXCR4/CXCL12 chemokine axis may play a critical role in guiding CXCR4+ circulating malignant cells to organ specific locations that actively secrete its ligand CXCL12 (SDF-1) such as bone, brain, liver, and lungs. We sought to chara...

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Bibliographic Details
Main Authors: Antecka Emilia, Logan Patrick, Fernandes Bruno F, Marshall Jean-Claude, Di Cesare Sebastian, Filho Vasco, Burnier Miguel N
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/7/1/17

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http://www.cancerci.com/content/7/1/17

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