Role of mammalian target of rapamycin signaling pathway in regulation of fatty acid oxidation in a preeclampsia-like mouse model treated with pravastatin

Abstract. Background:. Fatty acid oxidation (FAO) disorder is involved in the pathogenesis of some cases of preeclampsia (PE). Several studies show that mammalian target of rapamycin (mTOR) signaling pathway is related to FAO. Pravastatin (Pra) can promote FAO in Nω-nitro-L-arginine methyl ester (L...

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Bibliographic Details
Main Authors: Jing Huai, Zi Yang, Yan-Hong Yi, Guang-Jiao Wang, Ning-Ning Wang
Format: Article
Language:English
Published: Wolters Kluwer 2019-03-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000129