Inactivation of p15INK4b in chronic arsenic poisoning cases

Inactivation of p15INK4b in chronic arsenic poisoning cases

Arsenic exposure from burning high arsenic-containing coal has been associated with human skin lesion and cancer. However, the mechanisms of arsenic-related carcinogenesis are not fully understood. Inactivation of critical tumor suppression genes by epigenetic regulation or genetic modification migh...

Full description

Bibliographic Details
Main Authors: Aihua Zhang, Chen Gao, Xue Han, Lifang Wang, Chun Yu, Xiaowen Zeng, Liping Chen, Daochuan Li, Wen Chen
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
Arsenic
Domestic coal use
Skin lesions
p15INK4b
DNA methylation
Homozygous deletion
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000705

Internet

http://www.sciencedirect.com/science/article/pii/S2214750014000705

Similar Items