Sonic hedgehog promotes chondrogenesis of rabbit bone marrow stem cells in a rotary cell culture system

Abstract Background Sonic hedgehog (Shh) is an important signalling protein involved in the induction of early cartilaginous differentiation. Herein, we demonstrate that Shh markedly induces chondrogenesis of rabbit bone marrow stromal cells (BMSCs) under microgravity conditions, and promotes cartil...

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Bibliographic Details
Main Authors: Liyang Chen, Gejun Liu, Wenjun Li, Xing Wu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Developmental Biology
Subjects:
Shh
Online Access:http://link.springer.com/article/10.1186/s12861-019-0198-4