Chronic cerebral ischemia, neuroplasticity, possibilities of therapy
The paper presents current views on the pathogenetic mechanisms of cerebral ischemia. It discusses the role of neurotrophins in the processes of neuroplasticity. Experimental and clinical studies of the neuropeptide drug Cerebrolysin are reviewed. The authors describe in detail the results of the cl...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2017-07-01
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| Series: | Nevrologiâ, Nejropsihiatriâ, Psihosomatika |
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| Online Access: | https://nnp.ima-press.net/nnp/article/view/755 |
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doaj-06a5ba60fb9f49dcbacd88eac55fb8722021-07-29T08:58:38ZrusIMA-PRESS LLCNevrologiâ, Nejropsihiatriâ, Psihosomatika2074-27112310-13422017-07-019210210710.14412/2074-2711-2017-2-102-107666Chronic cerebral ischemia, neuroplasticity, possibilities of therapyE. I. Chukanova0A. S. Chukanova1N.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia, MoscowN.I. Pirogov Russian National Medical Research University, Ministry of Health of Russia, MoscowThe paper presents current views on the pathogenetic mechanisms of cerebral ischemia. It discusses the role of neurotrophins in the processes of neuroplasticity. Experimental and clinical studies of the neuropeptide drug Cerebrolysin are reviewed. The authors describe in detail the results of the clinical trial and a health economic analysis of the effects of Cerebrolysin on the time course of clinical changes, progression, and risk of exacerbations in patients with chronic cerebral ischemia.https://nnp.ima-press.net/nnp/article/view/755chronic cerebral ischemianeurodegenerationblood-brain barrieroxidative stressapoptosisneuroplasticityneurotrophic factorsneuroprotective drugscerebrolysin |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
E. I. Chukanova A. S. Chukanova |
| spellingShingle |
E. I. Chukanova A. S. Chukanova Chronic cerebral ischemia, neuroplasticity, possibilities of therapy Nevrologiâ, Nejropsihiatriâ, Psihosomatika chronic cerebral ischemia neurodegeneration blood-brain barrier oxidative stress apoptosis neuroplasticity neurotrophic factors neuroprotective drugs cerebrolysin |
| author_facet |
E. I. Chukanova A. S. Chukanova |
| author_sort |
E. I. Chukanova |
| title |
Chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| title_short |
Chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| title_full |
Chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| title_fullStr |
Chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| title_full_unstemmed |
Chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| title_sort |
chronic cerebral ischemia, neuroplasticity, possibilities of therapy |
| publisher |
IMA-PRESS LLC |
| series |
Nevrologiâ, Nejropsihiatriâ, Psihosomatika |
| issn |
2074-2711 2310-1342 |
| publishDate |
2017-07-01 |
| description |
The paper presents current views on the pathogenetic mechanisms of cerebral ischemia. It discusses the role of neurotrophins in the processes of neuroplasticity. Experimental and clinical studies of the neuropeptide drug Cerebrolysin are reviewed. The authors describe in detail the results of the clinical trial and a health economic analysis of the effects of Cerebrolysin on the time course of clinical changes, progression, and risk of exacerbations in patients with chronic cerebral ischemia. |
| topic |
chronic cerebral ischemia neurodegeneration blood-brain barrier oxidative stress apoptosis neuroplasticity neurotrophic factors neuroprotective drugs cerebrolysin |
| url |
https://nnp.ima-press.net/nnp/article/view/755 |
| work_keys_str_mv |
AT eichukanova chroniccerebralischemianeuroplasticitypossibilitiesoftherapy AT aschukanova chroniccerebralischemianeuroplasticitypossibilitiesoftherapy |
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1721250561882324992 |