Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis

Hedgehog regulates cerebellar progenitor cell and medulloblastoma apoptosis

The external granule layer (EGL) is a proliferative region that produces over 90% of the neurons in the cerebellum but can also malignantly transform into a cerebellar tumor called the medulloblastoma (the most common malignant brain tumor in children). Current dogma considers Hedgehog stimulation a...

Full description

Bibliographic Details
Main Authors: Kevin Kiyoshi Noguchi, Omar Hoseá Cabrera, Brant S. Swiney, Patricia Salinas-Contreras, Julie Kathryn Smith, Nuri B. Farber
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Neurobiology of Disease
Subjects:
Sonic Hedgehog
Cerebellum
Medulloblastoma
Apoptosis
External granule layer
Neural progenitor cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300425

Internet

http://www.sciencedirect.com/science/article/pii/S0969996115300425

Similar Items