Protective effects of 17β-estradiol on Benzo(e)pyrene[B(e)P]-induced toxicity in ARPE-19 cells

Protective effects of 17β-estradiol on Benzo(e)pyrene[B(e)P]-induced toxicity in ARPE-19 cells

Purpose: The aim of this study was to examine the effect of 17β-estradiol on Benzo(e)pyrene [B(e)P]-induced toxicity in ARPE-19 cells. Methods: We pretreated ARPE-19 cells with 20 nM and 40 nM 17β-estradiol for 6 hours, followed by addition of 300 μM B(e)P for additional 24 hours. Cell viability was...

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Bibliographic Details
Main Authors: Ashish U Sapkal, Sonali Nashine, Saffar Mansoor, Vishal R Sharma, Claudio A Ramirez, Rafael Z Migon, Navin K Gupta, Marilyn Chwa, Baruch D Kuppermann, Cristina Kenney
Format: Article
Language:English
Published: Knowledge E 2018-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
17β-Estradiol; Benzo(e)pyrene; Age-Related Macular Degeneration; Apoptosis; Retinal Pigment Epithelial Cells; Smoking
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2018;volume=13;issue=4;spage=419;epage=425;aulast=Sapkal

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