Dendritic calcium spikes are clearly detectable at the cortical surface

Dendritic calcium spikes are clearly detectable at the cortical surface

Surface EEG recordings are thought to primarily detect synaptic activity. Here the authors devise an optogenetic method to evoke dendritic calcium spikes in layer 5 pyramidal cells of the rat somatosensory cortex, and report that optogenetically evoked, as well as sensory-evoked dendritic calcium sp...

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Bibliographic Details
Main Authors: Mototaka Suzuki, Matthew E. Larkum
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00282-4
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spelling doaj-069ec5f4eac9423c919214701b7b285f2021-01-31T12:44:58ZengNature Publishing GroupNature Communications2041-17232017-08-018111110.1038/s41467-017-00282-4Dendritic calcium spikes are clearly detectable at the cortical surfaceMototaka Suzuki0Matthew E. Larkum1NeuroCure Cluster of Excellence, Department of Biology, Humboldt UniversityNeuroCure Cluster of Excellence, Department of Biology, Humboldt UniversitySurface EEG recordings are thought to primarily detect synaptic activity. Here the authors devise an optogenetic method to evoke dendritic calcium spikes in layer 5 pyramidal cells of the rat somatosensory cortex, and report that optogenetically evoked, as well as sensory-evoked dendritic calcium spikes make a significant contribution to surface EEG recordings.https://doi.org/10.1038/s41467-017-00282-4
collection DOAJ
language English
format Article
sources DOAJ
author Mototaka Suzuki
Matthew E. Larkum
spellingShingle Mototaka Suzuki
Matthew E. Larkum
Dendritic calcium spikes are clearly detectable at the cortical surface
Nature Communications
author_facet Mototaka Suzuki
Matthew E. Larkum
author_sort Mototaka Suzuki
title Dendritic calcium spikes are clearly detectable at the cortical surface
title_short Dendritic calcium spikes are clearly detectable at the cortical surface
title_full Dendritic calcium spikes are clearly detectable at the cortical surface
title_fullStr Dendritic calcium spikes are clearly detectable at the cortical surface
title_full_unstemmed Dendritic calcium spikes are clearly detectable at the cortical surface
title_sort dendritic calcium spikes are clearly detectable at the cortical surface
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-08-01
description Surface EEG recordings are thought to primarily detect synaptic activity. Here the authors devise an optogenetic method to evoke dendritic calcium spikes in layer 5 pyramidal cells of the rat somatosensory cortex, and report that optogenetically evoked, as well as sensory-evoked dendritic calcium spikes make a significant contribution to surface EEG recordings.
url https://doi.org/10.1038/s41467-017-00282-4
work_keys_str_mv AT mototakasuzuki dendriticcalciumspikesareclearlydetectableatthecorticalsurface
AT matthewelarkum dendriticcalciumspikesareclearlydetectableatthecorticalsurface
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