A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope

We have developed a new multichannel spectral imaging laser scanning confocal microscope for effective detection of multiple fluorescent labeling in the research of biological tissues. In this paper, the design and key technologies of the system are introduced. Representative results on confocal ima...

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Main Authors: Yunhai Zhang, Bian Hu, Yakang Dai, Haomin Yang, Wei Huang, Xiaojun Xue, Fazhi Li, Xin Zhang, Chenyu Jiang, Fei Gao, Jian Chang
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2013/890203
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spelling doaj-0697ff30fae24bf8b8fc049692d9b2362020-11-24T23:21:01ZengHindawi LimitedComputational and Mathematical Methods in Medicine1748-670X1748-67182013-01-01201310.1155/2013/890203890203A New Multichannel Spectral Imaging Laser Scanning Confocal MicroscopeYunhai Zhang0Bian Hu1Yakang Dai2Haomin Yang3Wei Huang4Xiaojun Xue5Fazhi Li6Xin Zhang7Chenyu Jiang8Fei Gao9Jian Chang10Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, ChinaWe have developed a new multichannel spectral imaging laser scanning confocal microscope for effective detection of multiple fluorescent labeling in the research of biological tissues. In this paper, the design and key technologies of the system are introduced. Representative results on confocal imaging, 3-dimensional sectioning imaging, and spectral imaging are demonstrated. The results indicated that the system is applicable to multiple fluorescent labeling in biological experiments.http://dx.doi.org/10.1155/2013/890203
collection DOAJ
language English
format Article
sources DOAJ
author Yunhai Zhang
Bian Hu
Yakang Dai
Haomin Yang
Wei Huang
Xiaojun Xue
Fazhi Li
Xin Zhang
Chenyu Jiang
Fei Gao
Jian Chang
spellingShingle Yunhai Zhang
Bian Hu
Yakang Dai
Haomin Yang
Wei Huang
Xiaojun Xue
Fazhi Li
Xin Zhang
Chenyu Jiang
Fei Gao
Jian Chang
A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
Computational and Mathematical Methods in Medicine
author_facet Yunhai Zhang
Bian Hu
Yakang Dai
Haomin Yang
Wei Huang
Xiaojun Xue
Fazhi Li
Xin Zhang
Chenyu Jiang
Fei Gao
Jian Chang
author_sort Yunhai Zhang
title A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
title_short A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
title_full A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
title_fullStr A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
title_full_unstemmed A New Multichannel Spectral Imaging Laser Scanning Confocal Microscope
title_sort new multichannel spectral imaging laser scanning confocal microscope
publisher Hindawi Limited
series Computational and Mathematical Methods in Medicine
issn 1748-670X
1748-6718
publishDate 2013-01-01
description We have developed a new multichannel spectral imaging laser scanning confocal microscope for effective detection of multiple fluorescent labeling in the research of biological tissues. In this paper, the design and key technologies of the system are introduced. Representative results on confocal imaging, 3-dimensional sectioning imaging, and spectral imaging are demonstrated. The results indicated that the system is applicable to multiple fluorescent labeling in biological experiments.
url http://dx.doi.org/10.1155/2013/890203
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