Preventive Agents for Migraine: Focus on the Antiepileptic Drugs

Preventive Agents for Migraine: Focus on the Antiepileptic Drugs

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Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophyl...

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Main Authors: R. Shahien, K. Beiruti
Format: Article
Language:English
Published: SAGE Publishing 2012-04-01
Series:Journal of Central Nervous System Disease
Online Access:https://doi.org/10.4137/JCNSD.S9049
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spelling doaj-068e55a502eb44ecbda91dd7a02aca182020-11-25T03:09:23ZengSAGE PublishingJournal of Central Nervous System Disease1179-57352012-04-01410.4137/JCNSD.S9049Preventive Agents for Migraine: Focus on the Antiepileptic DrugsR. Shahien0K. Beiruti1Department of Neurology, Ziv Medical Center, affiliated to Bar Ilan University, Safed 13100, Israel.Department of Neurology, Ziv Medical Center, affiliated to Bar Ilan University, Safed 13100, Israel.Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophylaxis with antiepileptic drugs. Particular focus is given to their mechanism of action, metabolism, pharmacokinetics, safety profile, efficacy and to provide a summary of the most relevant clinical studies and patient preference.https://doi.org/10.4137/JCNSD.S9049
collection DOAJ
language English
format Article
sources DOAJ
author R. Shahien
K. Beiruti
spellingShingle R. Shahien
K. Beiruti
Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
Journal of Central Nervous System Disease
author_facet R. Shahien
K. Beiruti
author_sort R. Shahien
title Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_short Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_full Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_fullStr Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_full_unstemmed Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_sort preventive agents for migraine: focus on the antiepileptic drugs
publisher SAGE Publishing
series Journal of Central Nervous System Disease
issn 1179-5735
publishDate 2012-04-01
description Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophylaxis with antiepileptic drugs. Particular focus is given to their mechanism of action, metabolism, pharmacokinetics, safety profile, efficacy and to provide a summary of the most relevant clinical studies and patient preference.
url https://doi.org/10.4137/JCNSD.S9049
work_keys_str_mv AT rshahien preventiveagentsformigrainefocusontheantiepilepticdrugs
AT kbeiruti preventiveagentsformigrainefocusontheantiepilepticdrugs
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