Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype

Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype

Head and neck squamous cell carcinoma (HNSCC) is broadly classified into HNSCC associated with human papilloma virus (HPV) infection, and HPV negative HNSCC, which is typically smoking-related. A subset of HPV negative HNSCCs occur in patients without smoking history, however, and these etiologicall...

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Bibliographic Details
Main Authors: K. Brennan, J.L. Koenig, A.J. Gentles, J.B. Sunwoo, O. Gevaert
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:EBioMedicine
Subjects:
Head and neck squamous cell carcinoma
etiological subtypes
CpG island methylator phenotype
Multi-omics data analysis
antiviral gene signature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417300841

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