IgGs-Abzymes from the Sera of Patients with Multiple Sclerosis Recognize and Hydrolyze miRNAs

IgGs-Abzymes from the Sera of Patients with Multiple Sclerosis Recognize and Hydrolyze miRNAs

Autoantibodies-abzymes hydrolyzing DNA, myelin basic protein, and oligosaccharides have been revealed in the sera of patients with multiple sclerosis (MS). In MS, specific microRNAs are found in blood and cerebrospinal fluid, which are characterized by increased expression. Autoantibodies, specifica...

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Bibliographic Details
Main Authors: Evgeny A. Ermakov, Evelina M. Kabirova, Valentina N. Buneva, Georgy A. Nevinsky
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
abzymes
miRNA recognition and hydrolysis
autoimmune reactions
Online Access:https://www.mdpi.com/1422-0067/22/6/2812

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