IFN-τ Mediated Control of Bovine Major Histocompatibility Complex Class I Expression and Function via the Regulation of bta-miR-148b/152 in Bovine Endometrial Epithelial Cells

IFN-τ Mediated Control of Bovine Major Histocompatibility Complex Class I Expression and Function via the Regulation of bta-miR-148b/152 in Bovine Endometrial Epithelial Cells

IFN-τ, a type I interferon produced by the trophoblasts of ruminants, has various important immune functions, including effects on the expression of major histocompatibility complex (MHC) class I (MHC-I). A previous study has reported that IFN-τ promotes the expression of MHC-I molecules on endometr...

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Bibliographic Details
Main Authors: Haichong Wu, Kangfeng Jiang, Shuai Guo, Jing Yang, Gan Zhao, Changwei Qiu, Ganzhen Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
IFN-τ
major histocompatibility complex class I
TLR4
bta-miR-148b/152
bovine endometrial epithelial cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00167/full

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