Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations

Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations

Sustained release of therapeutic agents into tumor cells is a potential approach to improve therapeutic efficacy, decrease side effects, and the drug administration frequency. Herein, we used the modified double-emulsion solvent evaporation (DSE) method to prepare a novel morphological paclitaxel (P...

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Bibliographic Details
Main Authors: Zongrui Zhang, Xinyu Wang, Binbin Li, Yuanjing Hou, Jing Yang, Li Yi
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
paclitaxel
morphological features
sustained release
antitumor efficacy
cancer therapy
Online Access:http://dx.doi.org/10.1080/10717544.2017.1422296

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