Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration

The article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD...

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Main Authors: M. Kuznietsova, T. Halenova, O. Savchuk
Format: Article
Language:English
Published: Taras Shevchenko National University of Kyiv 2016-11-01
Series:Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ
Subjects:
Online Access:http://biovestnik.com/index.php/biology/article/view/8
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spelling doaj-0656ce690d1c4a96a380ce09da9068c42020-11-24T22:15:29ZengTaras Shevchenko National University of KyivVìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ1728-27482308-80362016-11-01711313510.17721/1728_2748.2016.71.31-358Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administrationM. Kuznietsova0T. Halenova1O. Savchuk2Taras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivThe article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD 50 following its intragastric administration is greater than 2000 mg/kg). The study of extract sub-acute toxicity showed the increasing of relative liver and kidney weight, which may indicate the existence of adverse effects of the extract under the conditions of its long-term administration.http://biovestnik.com/index.php/biology/article/view/8dry extract, white bean, toxicity
collection DOAJ
language English
format Article
sources DOAJ
author M. Kuznietsova
T. Halenova
O. Savchuk
spellingShingle M. Kuznietsova
T. Halenova
O. Savchuk
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ
dry extract, white bean, toxicity
author_facet M. Kuznietsova
T. Halenova
O. Savchuk
author_sort M. Kuznietsova
title Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
title_short Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
title_full Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
title_fullStr Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
title_full_unstemmed Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
title_sort acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
publisher Taras Shevchenko National University of Kyiv
series Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ
issn 1728-2748
2308-8036
publishDate 2016-11-01
description The article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD 50 following its intragastric administration is greater than 2000 mg/kg). The study of extract sub-acute toxicity showed the increasing of relative liver and kidney weight, which may indicate the existence of adverse effects of the extract under the conditions of its long-term administration.
topic dry extract, white bean, toxicity
url http://biovestnik.com/index.php/biology/article/view/8
work_keys_str_mv AT mkuznietsova acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration
AT thalenova acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration
AT osavchuk acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration
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