Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration
The article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD...
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Taras Shevchenko National University of Kyiv
2016-11-01
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Series: | Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
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Online Access: | http://biovestnik.com/index.php/biology/article/view/8 |
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doaj-0656ce690d1c4a96a380ce09da9068c42020-11-24T22:15:29ZengTaras Shevchenko National University of KyivVìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ1728-27482308-80362016-11-01711313510.17721/1728_2748.2016.71.31-358Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administrationM. Kuznietsova0T. Halenova1O. Savchuk2Taras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivTaras Shevchenko National University of Kyiv, KyivThe article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD 50 following its intragastric administration is greater than 2000 mg/kg). The study of extract sub-acute toxicity showed the increasing of relative liver and kidney weight, which may indicate the existence of adverse effects of the extract under the conditions of its long-term administration.http://biovestnik.com/index.php/biology/article/view/8dry extract, white bean, toxicity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
M. Kuznietsova T. Halenova O. Savchuk |
spellingShingle |
M. Kuznietsova T. Halenova O. Savchuk Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ dry extract, white bean, toxicity |
author_facet |
M. Kuznietsova T. Halenova O. Savchuk |
author_sort |
M. Kuznietsova |
title |
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
title_short |
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
title_full |
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
title_fullStr |
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
title_full_unstemmed |
Acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
title_sort |
acute and sub-acute toxicity studies of an extract from white bean pods under the condition of its intragastric administration |
publisher |
Taras Shevchenko National University of Kyiv |
series |
Vìsnik: Kiïvsʹkij Nacìonalʹnij Unìversitet Imenì Tarasa Ševčenka. Bìologìâ |
issn |
1728-2748 2308-8036 |
publishDate |
2016-11-01 |
description |
The article is devoted to the studies of acute and sub-acute toxicity of dry extract from white bean (P. vulgaris) pods. The acute toxicity study of the extract was carried out according to the conventional classification of K.K Sidorov and showed that the extract refers to low-toxic substances (LD 50 following its intragastric administration is greater than 2000 mg/kg). The study of extract sub-acute toxicity showed the increasing of relative liver and kidney weight, which may indicate the existence of adverse effects of the extract under the conditions of its long-term administration. |
topic |
dry extract, white bean, toxicity |
url |
http://biovestnik.com/index.php/biology/article/view/8 |
work_keys_str_mv |
AT mkuznietsova acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration AT thalenova acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration AT osavchuk acuteandsubacutetoxicitystudiesofanextractfromwhitebeanpodsundertheconditionofitsintragastricadministration |
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1725794062066253824 |