Transfer of <it>in vivo </it>primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner

<p>Abstract</p> <p>Background</p> <p>CD4+ T helper type 2 (T<sub>H</sub>2) cells, their cytokines IL-4, IL-5 and IL-13 and the transcription factor STAT6 are known to regulate various features of asthma including lung inflammation, mucus production and airwa...

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Bibliographic Details
Main Authors: Keegan Achsah D, Smith Elizabeth P, Chapoval Svetlana P, Dasgupta Preeta
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/12/60