Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes

Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes

Objective: Leptin alleviates hyperglycemia in rodent models of Type 1 diabetes by activating leptin receptors within the central nervous system. Here we delineate whether non-canonical leptin signaling through the Creb-regulated transcriptional coactivator 1 (Crtc1) contributes to leptin-dependent i...

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Bibliographic Details
Main Authors:	Geun Hyang Kim, Andras Szabo, Emily M. King, Jennifer Ayala, Julio E. Ayala, Judith Y. Altarejos
Format:	Article
Language:	English
Published:	Elsevier 2015-03-01
Series:	Molecular Metabolism
Subjects:	Leptin Type 1 diabetes Glucose Hypothalamus Creb-regulated transcriptional coactivator 1
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877814002075

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