SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation

SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation

SAFE (Scan and Find Early) is a novel microwave imaging device intended for breast cancer screening and early detection. SAFE is based on the use of harmless electromagnetic waves and can provide relevant initial diagnostic information without resorting to X-rays. Because of SAFE’s harmless effect o...

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Main Authors: Aleksandar Janjic, Mehmet Cayoren, Ibrahim Akduman, Tuba Yilmaz, Emre Onemli, Onur Bugdayci, Mustafa Erkin Aribal
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Diagnostics
Subjects:
breast cancer
microwave imaging
early diagnosis
clinical study
Online Access:https://www.mdpi.com/2075-4418/11/3/533
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spelling doaj-06521005ab4d43b49e3bb898c10d021c2021-03-17T00:06:15ZengMDPI AGDiagnostics2075-44182021-03-011153353310.3390/diagnostics11030533SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical EvaluationAleksandar Janjic0Mehmet Cayoren1Ibrahim Akduman2Tuba Yilmaz3Emre Onemli4Onur Bugdayci5Mustafa Erkin Aribal6Mitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeyMitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeyMitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeyMitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeyMitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeyDepartment of Radiology, School of Medicine, Marmara University, Pendik, 34899 Istanbul, TurkeyMitos Medical Technologies, ITU Ayazaga Ari Teknokent 2-B Block 2-2-E, Maslak, 34469 Istanbul, TurkeySAFE (Scan and Find Early) is a novel microwave imaging device intended for breast cancer screening and early detection. SAFE is based on the use of harmless electromagnetic waves and can provide relevant initial diagnostic information without resorting to X-rays. Because of SAFE’s harmless effect on organic tissue, imaging can be performed repeatedly. In addition, the scanning process itself is not painful since breast compression is not required. Because of the absence of physical compression, SAFE can also detect tumors that are close to the thoracic wall. A total number of 115 patients underwent the SAFE scanning procedure, and the resultant images were compared with available magnetic resonance (MR), ultrasound, and mammography images in order to determine the correct detection rate. A sensitivity of 63% was achieved. Breast size influenced overall sensitivity, as sensitivity was lower in smaller breasts (51%) compared to larger ones (74%). Even though this is only a preliminary study, the results show promising concordance with clinical reports, thus encouraging further SAFE clinical studies.https://www.mdpi.com/2075-4418/11/3/533breast cancermicrowave imagingearly diagnosisclinical study
collection DOAJ
language English
format Article
sources DOAJ
author Aleksandar Janjic
Mehmet Cayoren
Ibrahim Akduman
Tuba Yilmaz
Emre Onemli
Onur Bugdayci
Mustafa Erkin Aribal
spellingShingle Aleksandar Janjic
Mehmet Cayoren
Ibrahim Akduman
Tuba Yilmaz
Emre Onemli
Onur Bugdayci
Mustafa Erkin Aribal
SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
Diagnostics
breast cancer
microwave imaging
early diagnosis
clinical study
author_facet Aleksandar Janjic
Mehmet Cayoren
Ibrahim Akduman
Tuba Yilmaz
Emre Onemli
Onur Bugdayci
Mustafa Erkin Aribal
author_sort Aleksandar Janjic
title SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
title_short SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
title_full SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
title_fullStr SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
title_full_unstemmed SAFE: A Novel Microwave Imaging System Design for Breast Cancer Screening and Early Detection—Clinical Evaluation
title_sort safe: a novel microwave imaging system design for breast cancer screening and early detection—clinical evaluation
publisher MDPI AG
series Diagnostics
issn 2075-4418
publishDate 2021-03-01
description SAFE (Scan and Find Early) is a novel microwave imaging device intended for breast cancer screening and early detection. SAFE is based on the use of harmless electromagnetic waves and can provide relevant initial diagnostic information without resorting to X-rays. Because of SAFE’s harmless effect on organic tissue, imaging can be performed repeatedly. In addition, the scanning process itself is not painful since breast compression is not required. Because of the absence of physical compression, SAFE can also detect tumors that are close to the thoracic wall. A total number of 115 patients underwent the SAFE scanning procedure, and the resultant images were compared with available magnetic resonance (MR), ultrasound, and mammography images in order to determine the correct detection rate. A sensitivity of 63% was achieved. Breast size influenced overall sensitivity, as sensitivity was lower in smaller breasts (51%) compared to larger ones (74%). Even though this is only a preliminary study, the results show promising concordance with clinical reports, thus encouraging further SAFE clinical studies.
topic breast cancer
microwave imaging
early diagnosis
clinical study
url https://www.mdpi.com/2075-4418/11/3/533
work_keys_str_mv AT aleksandarjanjic safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT mehmetcayoren safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT ibrahimakduman safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT tubayilmaz safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT emreonemli safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT onurbugdayci safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
AT mustafaerkinaribal safeanovelmicrowaveimagingsystemdesignforbreastcancerscreeningandearlydetectionclinicalevaluation
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