A transcription-centric model of SNP-age interaction.

Complex age-associated phenotypes are caused, in part, by an interaction between an individual's genotype and age. The mechanisms governing such interactions are however not entirely understood. Here, we provide a novel transcriptional mechanism-based framework-SNiPage, to investigate such inte...

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Bibliographic Details
Main Authors: Kun Wang, Mahashweta Basu, Justin Malin, Sridhar Hannenhalli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009427

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