Intestinal Epithelial Cells Regulate Gut Eotaxin Responses and Severity of Allergy

Intestinal Epithelial Cells Regulate Gut Eotaxin Responses and Severity of Allergy

Intestinal epithelial cells (IECs) are known to regulate allergic sensitization. We addressed the role of the intrinsic IKKβ signaling in IECs in the effector phase of allergy following oral allergen challenge and its impact on the severity of responses is poorly. Upon orally sensitization by co-adm...

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Bibliographic Details
Main Authors: Eunsoo Kim, Melanie Lembert, Ghaith M. Fallata, John C. Rowe, Tara L. Martin, Abhay R. Satoskar, Nicholas V. Reo, Oleg Paliy, Estelle Cormet-Boyaka, Prosper N. Boyaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
intestinal epithelial cells
allergy
eotaxins
NF-κB
eosinophils
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01692/full

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