Immunological Mechanisms in the Pathophysiology of Non-Alcoholic Steatohepatitis

Immunological Mechanisms in the Pathophysiology of Non-Alcoholic Steatohepatitis

Non-alcoholic steatohepatitis (NASH) is characterized by the presence of steatosis, inflammation and hepatocyte injury and constitutes hepatic manifestation of the metabolic syndrome. The pathogenesis of NASH is complex and implicates cross-talk between different metabolically active sites, such as...

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Bibliographic Details
Main Authors: Sven Francque, Peter Michielsen, Luisa Vonghia
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:International Journal of Molecular Sciences
Subjects:
non-alcoholic steatohepatitis (NASH)
innate immunity
adaptive immunity
adipokines
Online Access:http://www.mdpi.com/1422-0067/14/10/19867

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