Effect of an educational intervention on the number potential drug-drug interactions

Effect of an educational intervention on the number potential drug-drug interactions

Background: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. Methods: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (...

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Main Authors: Aigul Z. Mussina, Gaziza A. Smagulova, Galina V. Veklenko, Bibigul B. Tleumagambetova, Nazgul A. Seitmaganbetova, Aigul A. Zhaubatyrova, Lazzat M. Zhamaliyeva
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016419300556
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spelling doaj-06385988d6914754ae27298a68913ac92020-11-25T01:59:00ZengElsevierSaudi Pharmaceutical Journal1319-01642019-07-01275717723Effect of an educational intervention on the number potential drug-drug interactionsAigul Z. Mussina0Gaziza A. Smagulova1Galina V. Veklenko2Bibigul B. Tleumagambetova3Nazgul A. Seitmaganbetova4Aigul A. Zhaubatyrova5Lazzat M. Zhamaliyeva6Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Abulhair Khan Avenue, 21-1-30, Aktobe 030020, Kazakhstan; Corresponding author at: Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Maresyev str., 68, 030019 Aktobe, Kazakhstan.Department of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Alia Moldagulova Avenue, 47-84, Aktobe 030000, KazakhstanDepartment of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Eset Batyr Street, 109-1-8, Aktobe 030000, KazakhstanDepartment of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Almaty District, Residential Massif Kargaly, 2 Mikroroyon, 16v – 230, Aktobe 030000, KazakhstanDepartment of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, 131g Bokenbay Batyr Street – 126, Aktobe 030000, KazakhstanDepartment of Propedeutics of Internal Diseases and Clinical Pharmacology, West Kazakhstan Marat Ospanov State Medical University, Novatorov lane 1, Aktobe 030012, KazakhstanCenter for Family Medicine and Primary Care Research, West Kazakhstan Marat Ospanov State Medical University, Alia Moldagulova Avenue, 11B – 120, Aktobe 030019, KazakhstanBackground: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. Methods: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. Results: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. Conclusion: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals. Keywords: Pharmacotherapy, Drug-drug interaction, Education, Cardiologyhttp://www.sciencedirect.com/science/article/pii/S1319016419300556
collection DOAJ
language English
format Article
sources DOAJ
author Aigul Z. Mussina
Gaziza A. Smagulova
Galina V. Veklenko
Bibigul B. Tleumagambetova
Nazgul A. Seitmaganbetova
Aigul A. Zhaubatyrova
Lazzat M. Zhamaliyeva
spellingShingle Aigul Z. Mussina
Gaziza A. Smagulova
Galina V. Veklenko
Bibigul B. Tleumagambetova
Nazgul A. Seitmaganbetova
Aigul A. Zhaubatyrova
Lazzat M. Zhamaliyeva
Effect of an educational intervention on the number potential drug-drug interactions
Saudi Pharmaceutical Journal
author_facet Aigul Z. Mussina
Gaziza A. Smagulova
Galina V. Veklenko
Bibigul B. Tleumagambetova
Nazgul A. Seitmaganbetova
Aigul A. Zhaubatyrova
Lazzat M. Zhamaliyeva
author_sort Aigul Z. Mussina
title Effect of an educational intervention on the number potential drug-drug interactions
title_short Effect of an educational intervention on the number potential drug-drug interactions
title_full Effect of an educational intervention on the number potential drug-drug interactions
title_fullStr Effect of an educational intervention on the number potential drug-drug interactions
title_full_unstemmed Effect of an educational intervention on the number potential drug-drug interactions
title_sort effect of an educational intervention on the number potential drug-drug interactions
publisher Elsevier
series Saudi Pharmaceutical Journal
issn 1319-0164
publishDate 2019-07-01
description Background: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. Methods: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. Results: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. Conclusion: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals. Keywords: Pharmacotherapy, Drug-drug interaction, Education, Cardiology
url http://www.sciencedirect.com/science/article/pii/S1319016419300556
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