Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals

Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer’s Disease Individuals

This study investigated for the first time the genomewide DNA methylation changes of noncoding RNA genes in the temporal cortex samples from individuals with Alzheimer’s disease (AD). The methylome of 10 AD individuals and 10 age-matched controls were obtained using Illumina 450 K methylation array....

Full description

Bibliographic Details
Main Authors:	Darine Villela, Rodrigo F. Ramalho, Aderbal R. T. Silva, Helena Brentani, Claudia K. Suemoto, Carlos Augusto Pasqualucci, Lea T. Grinberg, Ana C. V. Krepischi, Carla Rosenberg
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Neural Plasticity
Online Access:	http://dx.doi.org/10.1155/2016/2584940

Similar Items

Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain
by: Darine Villela, et al.
Published: (2018-01-01)

Germline DNA copy number variation in individuals with Argyrophilic grain disease reveals CTNS as a plausible candidate gene
by: Darine Villela, et al.
Published: (2013-01-01)

Mining Novel Candidate Imprinted Genes Using Genome-Wide Methylation Screening and Literature Review
by: Adriano Bonaldi, et al.
Published: (2017-09-01)

Alterações genômicas e epigenômicas nas manifestações anatomopatológicas e cognitivas da doença de Alzheimer
by: Darine Christina Maia Villela
Published: (2014)

Alterações genômicas e epigenômicas nas manifestações anatomopatológicas e cognitivas da doença de Alzheimer
by: Villela, Darine Christina Maia
Published: (2014)

Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease.
by: Aderbal R T Silva, et al.
Published: (2012-01-01)

Alzheimer and vascular brain disease: Senile dementia
by: Eliasz Engelhardt, et al.

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease
by: Sukriti Nag, et al.
Published: (2018-05-01)

The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer’s Disease
by: Xiaocong Pang, et al.
Published: (2017-01-01)

B and T Lymphocyte Densities Remain Stable With Age in Human Cortex
by: Kacey Berry, et al.
Published: (2021-05-01)

Alzheimer and vascular brain diseases: Focal and diffuse subforms
by: Eliasz Engelhardt, et al.

Alois Alzheimer and vascular brain disease: Arteriosclerotic atrophy of the brain
by: Eliasz Engelhardt, et al.

Quantitative comparison of different iron forms in the temporal cortex of Alzheimer patients and control subjects
by: Marjolein Bulk, et al.
Published: (2018-05-01)

Epitranscriptomic Alterations in Alzheimer’s Disease: The Role of MicroRNA Methylation in the Regulation of Tau Proteostasis
by: Kim, Yoon Anna
Published: (2021)

Temporal selectivity declines in the aging human auditory cortex
by: Julia Erb, et al.
Published: (2020-07-01)

EAAT2 Expression in the Hippocampus, Subiculum, Entorhinal Cortex and Superior Temporal Gyrus in Alzheimer’s Disease
by: Jason H. Y. Yeung, et al.
Published: (2021-09-01)

Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex
by: Purnima P. Desai, et al.
Published: (2005-11-01)

MicroRNA and mRNA profiling of cerebral cortex in a transgenic mouse model of Alzheimer’s disease by RNA sequencing
by: Li Zeng, et al.
Published: (2021-01-01)

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
by: Lanyu Zhang, et al.
Published: (2020-11-01)

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex
by: Gilles Gasparoni, et al.
Published: (2018-07-01)

MicroRNAs in Alzheimer’s Disease
by: Mengli Wang, et al.
Published: (2019-03-01)

MicroRNAs in Alzheimer's disease
by: Charlotte Delay, et al.
Published: (2012-05-01)

Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer’s Disease Brain
by: Ramasamy Thangavel, et al.
Published: (2017-05-01)

Assessments of the accumulation severities of amyloid β-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains
by: Xin-Wen Zhou, et al.
Published: (2006-06-01)

The Regulation of microRNAs in Alzheimer's Disease
by: Xianjuan Kou, et al.
Published: (2020-04-01)

Immune transcriptome alterations in the temporal cortex of subjects with autism
by: Krassimira Garbett, et al.
Published: (2008-06-01)

A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
by: Rebecca G. Smith, et al.
Published: (2021-06-01)

Síntese de melatonina na glândula pineal de ratos: modulação pelo glutamato.
by: Darine Christina Maia Villela
Published: (2008)

Síntese de melatonina na glândula pineal de ratos: modulação pelo glutamato.
by: Villela, Darine Christina Maia
Published: (2008)

Using individualized brain network for analyzing structural covariance of the cerebral cortex in Alzheimer’s patients
by: Hee-Jong Kim, et al.
Published: (2016-09-01)

microRNA profiles in Parkinson’s disease prefrontal cortex
by: Andrew G Hoss, et al.
Published: (2016-03-01)

Temporal production signals in parietal cortex.
by: Blaine A Schneider, et al.
Published: (2012-01-01)

Perirhinal cortex and temporal lobe epilepsy
by: Giuseppe eBiagini, et al.
Published: (2013-08-01)

Distinct transcriptome expression of the temporal cortex of the primate Microcebus murinus during brain aging versus Alzheimer's disease-like pathology.
by: Ronza Abdel Rassoul, et al.
Published: (2010-01-01)

Cellular Expression of α7 Nicotinic Acetylcholine Receptor Protein in the Temporal Cortex in Alzheimer's and Parkinson's Disease— A Stereological Approach
by: Carolin Banerjee, et al.
Published: (2000-12-01)

Cellular Expression of α7 Nicotinic Acetylcholine Receptor Protein in the Temporal Cortex in Alzheimer's and Parkinson's Disease—A Stereological Approach
by: Carolin Banerjee, et al.
Published: (2001-04-01)

Neuroinflammation is increased in the parietal cortex of atypical Alzheimer’s disease
by: Baayla D. C. Boon, et al.
Published: (2018-05-01)

Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease
by: Nienke M.E. Scheltens, et al.
Published: (2018-01-01)

Severe Dementia Predicts Weight Loss by the Time of Death
by: Aline Maria M. Ciciliati, et al.
Published: (2021-05-01)

Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease
by: Julie C. Lauterborn, et al.
Published: (2021-05-01)