DNA Double Strand Break Repair and its Association with Inherited Predispositions to Breast Cancer
<p>Abstract</p> <p>Mutations in <it>BRCA1 </it>account for the majority of familial aggregations of early onset breast and ovarian cancer (~70%) and about 1/5 of all early onset breast cancer families; in contrast, mutations in <it>BRCA2 </it>account for a s...
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Format: | Article |
Language: | English |
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BMC
2004-02-01
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Series: | Hereditary Cancer in Clinical Practice |
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Online Access: | http://www.hccpjournal.com/content/2/1/37 |