DNA Double Strand Break Repair and its Association with Inherited Predispositions to Breast Cancer

<p>Abstract</p> <p>Mutations in <it>BRCA1 </it>account for the majority of familial aggregations of early onset breast and ovarian cancer (~70%) and about 1/5 of all early onset breast cancer families; in contrast, mutations in <it>BRCA2 </it>account for a s...

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Bibliographic Details
Main Author: Scott Rodney J
Format: Article
Language:English
Published: BMC 2004-02-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://www.hccpjournal.com/content/2/1/37