Distinct patterns of interleukin-12/23 and tumor necrosis factor α synthesis by activated macrophages are modulated by glucose and colon cancer metabolites
Chronic inflammation is a major risk factor for colitis-associated colorectal carcinoma (CRC). Macrophages play a key role in altering the tumor microenvironment by producing pro-inflammatory and anti-inflammatory cytokines. Our previous studies showed that glucose metabolism conferred death resista...
Main Authors: | Ching-Ying Huang, Linda Chia-Hui Yu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2020-01-01
|
Series: | Chinese Journal of Physiology |
Subjects: | |
Online Access: | http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2020;volume=63;issue=1;spage=7;epage=14;aulast=Huang |
Similar Items
-
Defining murine monocyte differentiation into colonic and ileal macrophages
by: Mor Gross-Vered, et al.
Published: (2020-01-01) -
Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis
by: Catrin Youssif, et al.
Published: (2018-07-01) -
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
by: Yan-Jiun Huang, et al.
Published: (2017-02-01) -
Regulations of Glycolytic Activities on Macrophages Functions in Tumor and Infectious Inflammation
by: Qing Yu, et al.
Published: (2020-06-01) -
MicroRNA-4284 inhibits colon cancer epithelial-mesenchymal transition by down-regulating Perilipin 5
by: Xiaofei Miao, et al.
Published: (2021-03-01)