Hepatitis C virus infection in hemodialysis patients in Maracaibo, Venezuela

Over a two year period, the incidence of hepatitis C virus (HCV) infection was evaluated in 29 hemodialysis patients, aged between 15 and 75 years (mean ± SD: 45 ± 39.5 years), from the University Hospital Hemodyalisis Unit, Maracaibo, Zulia State, Venezuela. Anti-HCV antibodies were determined usin...

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Bibliographic Details
Main Authors: Francisca Monsalve-Castillo, Liliana Gómez-Gamboa, Leonor Chacín-Bonilla, Leticia Porto-Espinoza, Luciana Costa-León
Format: Article
Language:English
Published: Universidade de São Paulo 2012-02-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652012000100010&lng=en&tlng=en
Description
Summary:Over a two year period, the incidence of hepatitis C virus (HCV) infection was evaluated in 29 hemodialysis patients, aged between 15 and 75 years (mean ± SD: 45 ± 39.5 years), from the University Hospital Hemodyalisis Unit, Maracaibo, Zulia State, Venezuela. Anti-HCV antibodies were determined using a fourth generation ELISA (Innotest HCV Ab IV) kit and positive blood samples were tested using a recombinant assay kit (Inno-LIA HCV Ab III), both kits from Innogenetics N.V., Belgium. The findings indicate a lack of HCV seroconversion in the hemodialysis patients over the study period, confirmed by the recombinant assay. Risk factors for HCV infection were 0.3270 (95% confidence interval: 0.01323-8.080) in patients undergoing hemodialysis. The findings suggest a lack of significant sources for HCV infection due to the preventive measures to avoid its transmission in the hemodialysis unit.
ISSN:1678-9946