Advanced adenomas may be a red flag for hereditary cancer syndromes

Advanced adenomas may be a red flag for hereditary cancer syndromes

Abstract Background 16–25% of colorectal cancers (CRCs) diagnosed under age 50 are associated with hereditary cancer syndromes. Advanced adenomas are considered precursors to CRC. Although polyp removal prevents cancer, polypectomy does not change underlying genetic risk. Patients with isolated adva...

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Bibliographic Details
Main Authors: Swati G. Patel, Heather Hampel, Derek Smith, Dexiang Gao, Myles Cockburn, Fay Kastrinos
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Colorectal cancer
Colorectal polyps
Adenomas
Genetic testing
Lynch syndrome
Online Access:https://doi.org/10.1186/s13053-020-00164-9

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