An Efficient Approach for Lipase-Catalyzed Synthesis of Retinyl Laurate Nutraceutical by Combining Ultrasound Assistance and Artificial Neural Network Optimization

An Efficient Approach for Lipase-Catalyzed Synthesis of Retinyl Laurate Nutraceutical by Combining Ultrasound Assistance and Artificial Neural Network Optimization

Although retinol is an important nutrient, retinol is highly sensitive to oxidation. At present, some ester forms of retinol are generally used in nutritional supplements because of its stability and bioavailability. However, such esters are commonly synthesized by chemical procedures which are harm...

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Bibliographic Details
Main Authors: Shang-Ming Huang, Hsin-Ju Li, Yung-Chuan Liu, Chia-Hung Kuo, Chwen-Jen Shieh
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
retinol
lipase
retinyl laurate
sonication
artificial neural network (ANN)
central composite design
Online Access:https://www.mdpi.com/1420-3049/22/11/1972

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