Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery
The interaction of nanoparticles with a range of biomolecules once they have been injected within the body can affect their performance. Here, the authors demonstrate that squalene nanomaterials conjugated with anticancer drugs can interact with lipoproteins and can be used to target cancer cells.
Bibliographic Details
| Main Authors: |
Dunja Sobot,
Simona Mura,
Semen O. Yesylevskyy,
Laura Dalbin,
Fanny Cayre,
Guillaume Bort,
Julie Mougin,
Didier Desmaële,
Sinda Lepetre-Mouelhi,
Grégory Pieters,
Bohdan Andreiuk,
Andrey S. Klymchenko,
Jean-Louis Paul,
Christophe Ramseyer,
Patrick Couvreur |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2017-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms15678
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