In silico ADME in drug design – enhancing the impact

In silico ADME in drug design – enhancing the impact

Each year the pharmaceutical industry makes thousands of compounds, many of which do not meet the desired efficacy or pharmacokinetic properties, describing the absorption, distribution, metabolism and excretion (ADME) behavior. Parameters such as lipophilicity, solubility and metabolic stability ca...

Full description

Bibliographic Details
Main Authors: Susanne Winiwarter, Ernst Ahlberg, Edmund Watson, Ioana Oprisiu, Mickael Mogemark, Tobias Noeske, Nigel Greene
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2018-03-01
Series:ADMET and DMPK
Subjects:
Drug discovery
pharmacokinetics
in silico predictions
multi-parameter ranking
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/470

Similar Items

Similar Items