Tissue Plasminogen Activator and MRI Signs of Cerebral Small Vessel Disease

Tissue Plasminogen Activator and MRI Signs of Cerebral Small Vessel Disease

Cerebral small vessel disease (SVD) is one of the leading causes of cognitive impairment and stroke. The importance of endothelial dysfunction and high blood−brain barrier (BBB) permeability in pathogenesis, together with ischemia, is under discussion. The aim of this study was to clarify...

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Bibliographic Details
Main Authors:	Larisa A. Dobrynina, Alla A. Shabalina, Maryam R. Zabitova, Elena I. Kremneva, Zukhra Sh. Gadzhieva, Marina V. Krotenkova, Elena V. Gnedovskaya, Alexander B. Berdalin, Lyudmila A. Kalashnikova
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Brain Sciences
Subjects:	cerebral small vessel disease white matter hyperintensities perivascular spaces endothelial dysfunction tissue plasminogen activator blood–brain barrier
Online Access:	https://www.mdpi.com/2076-3425/9/10/266

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