The Effect of CAG Repeats within the Non-Pathological Range in the HTT Gene on Cognitive Functions in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

The Effect of CAG Repeats within the Non-Pathological Range in the HTT Gene on Cognitive Functions in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

The Huntingtin gene (HTT) is within a class of genes containing a key region of CAG repeats. When expanded beyond 39 repeats, Huntington disease (HD) develops. Individuals with less than 35 repeats are not associated with HD. Increasing evidence has suggested that CAG repeats play a role in modulati...

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Bibliographic Details
Main Authors: Valentina Bessi, Salvatore Mazzeo, Silvia Bagnoli, Giulia Giacomucci, Assunta Ingannato, Camilla Ferrari, Sonia Padiglioni, Virginia Franchi, Sandro Sorbi, Benedetta Nacmias
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Diagnostics
Subjects:
subjective cognitive decline
mild cognitive impairment
Huntington’s gene
CAG repeats
intermediate alleles
cognitive functions
Online Access:https://www.mdpi.com/2075-4418/11/6/1051

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